Articles

PP2.5 Hypercoagulability in adult sickle cell patients as compared to sickle cell trait subjects and a control group

BJH - volume 7, issue Abstract Book BHS, january 2016

B. Mahadeb , D. Noubouossie MD, L. Rozen PharmD, T. Besse-Hamme , A. Efira MD, P. Hermans MD, PhD, B. Gulbis MD, PhD, M.A. Azerad MD, A. Demulder MD, PhD

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Thrombin generation in the plasma of sickle cell trait adults shows prothrombotic profile as compared to normal adults

BJH - 2014, issue Abstract Book BSTH, november 2014

L. Dewispelaere MD, B. Mahadeb , L. Rozen PharmD, D. Noubouossie MD, T. Besse-Hamer , A. Efira MD, P. Hermans MD, PhD, B. Gulbis MD, PhD, M.A. Azerad MD, A. Demulder MD, PhD

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The place of the determination of D-dimer and its improvement

BJH - volume 4, issue 2, june 2013

L. Rozen PharmD, D. Noubouossie MD, A. Demulder MD, PhD

Summary

D–dimer (DD) assay is a widely used laboratory test in thrombosis-related conditions because it is rapid and easy to perform. This test is highly sensitive to thrombus formation and degradation. However DD levels are increased in many clinical conditions so that its positive predictive value is poor. Improvements of its usefulness have been mainly realised by combining the test with clinical scores and by adapting positive threshold to particular settings of patients. In this article, different methods of DD testing are presented with the aim to review their benefits and pitfalls in various clinical applications.

(BELG J HEMATOL 2013;4(2):47–50)

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P.51 Relationship between thrombin generation and blood flow velocity in large cerebral arteries of children with sickle cell disease

BJH - 2013, issue BHS Abstractbook, january 2013

D. Noubouossie MD, F. Ziereisen , P.-Q. Le , D. Willems , B. Mahadeb , L. Rozen PharmD, M. Ngalula Mujinga , A. Demulder MD, PhD, A. Ferster MD, PhD

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