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E. Van den Neste MD, PhD

Articles

P.25 Ibrutinib-induced acrocyanosis

BJH - volume 11, issue Abstract Book BHS, february 2020

I. Dufour , G. Verstraete MD, J. Raedemaeker , F. Andreozzi , L. Bamps , S. Chabert , A. Sogorb , S. Bailly MD, E. Van den Neste MD, PhD, X. Theunssens , F. Tamirou , D. Tennstedt , A. Camboni MD, PhD, M.C. Vekemans MD

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BHS guidelines for the treatment of marginal zone lymphomas: 2018 update

BJH - volume 10, issue 4, june 2019

D. Bron MD, PhD, M. Maerevoet MD, E. Van den Neste MD, PhD, V. Delrieu MD, F. Offner MD, PhD, W. Schroyens MD, PhD, A. Van Hoof MD, PhD, G. Verhoef MD, PhD, J.B. Giot MD, J.P. Loly MD, A. Janssens MD, PhD, C. Bonnet MD

Marginal zone lymphomas (MZL) are a heterogeneous subtype of indolent B-non-Hodgkin lymphomas that includes distinct entities:

  • Extranodal mucosa-associated lymphoid tissue lymphoma arises in a variety of tissue but primarily in the stomach. They are usually localised and often associated with chronic antigenic stimulation by microbial pathogens. Eradication of the pathogen is a major part of the first-line therapy. The prognosis is excellent in early stages. In advanced stages, observation, anti-CD20 antibodies and/or cytostatic drugs are therapeutical approaches.
  • Nodal MZL is usually confined in lymph nodes, bone marrow and peripheral blood. The prognosis is somewhat worse in this entity. Current recommendations suggest that they should be managed as follicular lymphomas.
  • Splenic MZL is a unique entity involving the spleen, bone marrow and blood. Hepatitis infection should be eradicated before considering treatment. These lymphomas have an indolent behaviour, and only symptomatic patients should be treated by splenectomy and/or anti-CD20 antibodies.
  • Two novel entities are described, non-chronic lymphocytic leukaemia monoclonal B-cell lymphocytosis, probably closely related to splenic MZL lymphoma, and a less well-defined provisional entity involving primarily the spleen called splenic B-cell lymphoma/leukaemia, unclassifiable, including splenic diffuse red pulp lymphoma and hairy-cell leukaemia variant.

This review will discuss separately the diagnosis, work-up and treatment of extranodal mucosa-associated lymphoid tissue lymphoma, nodal MZL and splenic MZL. These guidelines include the recently published ESMO consensus conference on malignant lymphoma.1–3

(BELG J HEMATOL 2019;10(4):153–64)

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The 4th LYSA meeting

BJH - volume 9, issue 5, september 2018

C. Bonnet MD, M.C. Ngirabacu , M. Maerevoet MD, V. De Wilde MD, PhD, E. Van den Neste MD, PhD, M. André MD, PhD

SUMMARY

The 4th edition of the LYSA meeting was organised by Professor Steven Legouill’s team and held in Nantes from the 8th to 10th February, 2018. It was a real opportunity for the 500 participants to learn novelties on lymphoma and to be updated on ongoing clinical trials conducted by this cooperative group. All the presentations were outstanding and gave us new indications on how to better treat our patients in the near future.

(BELG J HEMATOL 2017;9(5):195–8)

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P29 Breast implants: a rare cause of anaplastic large T-cell lymphoma

BJH - 2018, issue Abstract Book BHS, february 2018

S. Bailly MD, Y. Breners , S. Amat , L. Maindiaux , F. Dall’Armellina , C. Galant , A. Camboni MD, PhD, M. Coyette , E. Van den Neste MD, PhD, M.C. Vekemans MD

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PP06 Hereditary predisposition syndromes to malignant hemopathies (HPSMH)

BJH - 2018, issue Abstract Book BHS, february 2018

S. Dupriez , A. Ferrant , M.C. Vekemans MD, B. Brichard MD, PhD, L. Michaux MD, PhD, T. Connerotte MD, E. Van den Neste MD, PhD, C. Vermylen , L. Knoops MD, PhD, C. Graux MD, PhD, F. Duhoux MD, PhD, C. Lambert MD, PhD, X. Poiré MD, PhD, H.A. Poirel MD, PhD

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O6 Analysis of the impact of mismatches at HLA loci DRB3/4/5 on outcomes after allogeneic stem cell transplantation

BJH - 2018, issue Abstract Book BHS, february 2018

F. Van Obbergh MD, N. Vanlangendonck , A. Van Maanen , P. Van Muylder , A. Ferrant , C. Lambert MD, PhD, E. Van den Neste MD, PhD, D. Latinne , X. Poiré MD, PhD

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P79 Atypical bone pain after allogeneic bone marrow transplantation for myelofibrosis

BJH - volume 8, issue Abstract Book BHS, february 2017

G. Verstraete MD, S. Lefevre , S. Bailly MD, G. Di Prinzio , J. Devreux , J-P. Defour PhD, P. D’Abadie , P. Van Eeckhout , F. Kino , C. Goemare , N. Lepage , L. Michaux MD, PhD, V. Havelange MD, PhD, E. Van den Neste MD, PhD, C. Lambert MD, PhD, L. Knoops MD, PhD, M.C. Vekemans MD, X. Poiré MD, PhD

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