Articles

Vaccine response in patients receiving anti-B-cell targeted therapy

BJH - volume 9, issue 3, june 2018

N. De Wilde , F. Offner MD, PhD

SUMMARY

Infection prevention is of major importance in patients with haematological malignancies, who are immunocompromised because of disease-related and therapy-related factors. However, in patients receiving anti-B-cell therapies, such as rituximab or ibrutinib (an irreversible BTK inhibitor), measures for infection prevention are hardly studied. In this review we considered vaccine response in patients receiving rituximab treatment and we investigated if an adequate vaccine response can be achieved in patients treated with ibrutinib. For rituximab, no protective titers are obtained in patients with haematological malignancies, but in rheumatoid arthritis 30–50% of patients achieve protective titres. Vaccine response following ibrutinib seems low but it is insufficiently studied to make evidence based recommendations.

(BELG J HEMATOL 2018;9(3):113–7)

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P36 Can CLL-IPI at time of diagnosis predict who may never need treatment for B-CLL?

BJH - 2018, issue Abstract Book BHS, february 2018

V. Galle MD, P. Vlummens MD, F. Offner MD, PhD

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P45 Donor cell derived deletion 7q occurring after allogeneic stem cell transplantation: a case report

BJH - 2018, issue Abstract Book BHS, february 2018

dr. A. Delie MD, P. Vlummens MD, N. Van Roy PhD, F. Offner MD, PhD, T. Kerre MD, PhD

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PP24 Is it possible to create an index that can predict who may never need treatment for B-CLL?

BJH - 2018, issue Abstract Book BHS, february 2018

V. Galle MD, P. Vlummens MD, F. Offner MD, PhD

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PP21 The light chain IgLV3-21 defines a new poor prognostic subgroup in Chronic Lymphocytic Leukemia: results from a multicenter study

BJH - 2018, issue Abstract Book BHS, february 2018

B. Stamatopoulos , T. Smith , E. Crompot , K. Pieters , R. Clifford , M. Mraz , P. Robbe , A. Burns , A. Timbs , D. Bruce , P. Hillmen , N. Meuleman MD, PhD, P. Mineur MD, R. Firescu , M. Maerevoet MD, V. De Wilde MD, PhD, A. Efira MD, J. Philippé MD, PhD, B. Verhasselt MD, PhD, F. Offner MD, PhD, A. Heger , D. Sims , H. Dreau , A. Schuh

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P14 The impact of the updated IMWG diagnostic criteria in a real-life SMM cohort: a single center experience

BJH - volume 8, issue Abstract Book BHS, february 2017

P. Vlummens MD, F. Offner MD, PhD

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P17 Diagnostic strength of bone marrow aspirate versus biopsy in (smoldering) multiple myeloma patients

BJH - volume 8, issue Abstract Book BHS, february 2017

P. Vlummens MD, F. Offner MD, PhD

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