BJH - 2019, issue ?, february 2019
J. Beekwilder PhD, T. Feys MBA, MSc
At the time of the introduction of direct oral anticoagulants (DOACs) in the beginning of this century, episodic and routine monitoring of these drug concentrations was deemed unnecessary. Unlike oral vitamin K anticoagulation, DOACs showed predictable pharmacokinetics and pharmacodynamics. However, once in clinical practice it became clear that under specific circumstances predictability of drug concentrations was less than optimal. During his educational presentation, Prof Johathan Douxfils (Univeristy of Namur) provided some answers to the questions why, when, and how we should measure DOAC concentrations.
Read moreBJH - 2019, issue ?, february 2019
J. Beekwilder PhD, T. Feys MBA, MSc
With “Looking back at the history of haemostasis with a sneak peek into the future”, Marc Hoylaerts (Center for Molecular and Vascular Biology, KU Leuven, LEUVEN, Belgium) gave his personal view on the field of haemostasis. He did this in the lecture in memory of and named after Professor Gaston Baele, who became the first president of the BSTH over 25 years ago.
Read moreBJH - 2019, issue ?, february 2019
J. Beekwilder PhD, T. Feys MBA, MSc
Starting off the second day of the annual meeting of the BSTH, Andreas Greinacher (Greifswald, Germany) presented on the mechanism behind heparin-induced thrombocytopenia (HIT). A mechanism that is part of an evolutionary old defence mechanism against prokaryotic pathogens. However, when misdirected this pathway displays an until recently unknown mechanism of autoimmunity.
Read moreBJH - 2019, issue ?, february 2019
J. Beekwilder PhD, T. Feys MBA, MSc
The coagulation system is rarely left alone. Microorganisms, both harmless and harmful, can affect the function of the system, which can have clinical consequences of variable severity. The second State of the art session, entitled “microorganisms as an environmental factor”, chaired by prof. Simon De Meyer and dr. Muriel Sprynger featured several presentations on the interactions between these small lifeforms and thrombosis and haemostasis.
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