Articles

PP41 The role of myeloid-derived suppressor cells in autologous hematopoietic stem cell transplantation

BJH - 2018, issue Abstract Book BHS, february 2018

A. Betsch , O. Rutgeerts , S. Fevery MD, PhD, B. Sprangers MD, PhD, D. Dierickx MD, PhD, M. Beckers MD, PhD

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The role of myeloid-derived suppressor cells in haematology: hype or reality?

BJH - volume 7, issue 6, december 2016

M. Beckers MD, PhD, D. Dierickx MD, PhD, T. Devos MD, PhD, S. Fevery MD, PhD, B. Sprangers MD, PhD

Summary

One of the hallmarks of failure of elimination of malignant cells by activated T-cells is the immunosuppressive environment of the tumour. Myeloid-derived suppressor cells contribute to this immunosuppressive environment by inhibition of the adaptive and innate immune system. In this article we describe the current knowledge of the role of myeloid-derived suppressor cells in the progression of haematological malignancies.

(BELG J HEMATOL 2016;7(6):213–6)

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