BJH - 2022, issue SPECIAL, april 2022
A. Enguita PhD, T. Feys MBA, MSc
High-risk haematology patients present with a partial or totally disintegrated immune system. Consequently, infections remain one of the main causes of morbidity and mortality among these patients. During the 37th general annual meeting of the Belgian Haematology Society, Prof. Johan Maertens (University Hospital Leuven, Leuven, Belgium), walked us through the current advances in the management of infections in high-risk haematology patients, with a focus on patients undergoing aggressive chemotherapy for any type of leukaemia and allogenic non-transplanted siblings.
Read moreBJH - 2022, issue SPECIAL, april 2022
J. Blokken PhD, PharmD, T. Feys MBA, MSc
The Belgian Society of Human Genetics (BeSHG) was launched in March 2000 and aims at promoting human genetics in its wider sense, i.e. by supporting genetic research, improving exchanges between Belgium and foreign countries, organising scientific meetings, and enhancing collaboration between Belgian labs. During the 37th general annual meeting of the Belgian Haematology Society, a joint BeSHG-BHS session was organised. In this session, Karlijn Brekelmans (University Hospital Leuven, Leuven, Belgium) first discussed how genetic predisposition in haemato-oncological disorders can be detected, with a focus on technique, type of tissue that can be used and turn-around-time. Her talk was followed by a presentation from Esmé Waanders (Princess Maxima Centre, Utrecht, The Netherlands) discussing geentic predisposition in lymphoid malignancies.
Read moreBJH - 2022, issue SPECIAL, april 2022
A. Enguita PhD, T. Feys MBA, MSc
Myelofibrosis (MF) is a chronic malignancy characterised by marrow fibrosis and myeloproliferation caused by a constitutive activation of the Janus-activated kinase (JAK) transcription signalling pathway. This constitutive activation is usually the result of mutations in the driver genes JAK2, myeloproliferative leukaemia virus (MPL) or calreticulin (CALR).1 The most important clinical manifestation of MF consists of splenomegaly, in addition to hepatomegaly, cytopenia (mainly anaemia), and constitutional symptoms.2 MF significantly decreases the life expectancy of patients with a median survival of less than six years.3 During the 37th general annual meeting of the Belgian Haematology Society, professor Jean-Jacques Kiladjian (Saint Louis Hospital, Paris, France) discussed the contemporary management of this disease.
Read moreBJH - 2021, issue SPECIAL, january 2021
prof. F. Baron
During the the 36th general annual meeting of the Belgian Haematology Society prof. Frédéric Baron addressed an interesting question; which conditioning regimen should be chosen for which acute myeloid leukaemia (AML) patient? As you will find out in this report, the answer to this question is not so straight forward.
Read moreBJH - 2021, issue SPECIAL, january 2021
prof. M.V. Mateos
Multiple myeloma (MM) is a clonal plasma cell malignancy affecting a predominantly elderly population. The continued development of newer therapies with novel mechanisms of action has reshaped the treatment paradigm of this disorder in the last two decades, leading to a significantly improved prognosis. Immune-based therapies, including monoclonal antibodies, and more recently also adoptive cellular therapies have emerged as therapeutic strategies in MM. During her lecture at the 2021 BHS GAM, Prof. Maria-Victoria Mateos gave an overview of the current state of affairs related to immune related therapies in MM.
Read moreBJH - 2021, issue SPECIAL, january 2021
T. Mercier MD, PhD
The global COVID-19 pandemic had a major impact on all the aspects of the healthcare system and hematology departments were no exception to this. In order to get more insights into the risk for severe COVID-19 infections among patients with hematological conditions, the Belgian Hematology Society set up the BHS COVID-19 registry. During the 2021 BHS general annual meeting preliminary results of this registry were presented.
Read moreBJH - 2021, issue SPECIAL, january 2021
Prof J. Apperley
The therapeutic landscape of chronic myeloid leukaemia (CML) has changed dramatically over the past decades and the majority of patients with Philadelphia chromosome-positive (Ph+) CML in chronic phase (CP) now have a near-normal life expectancy.1 Based on two recent published guidelines (European LeukemiaNet (ELN) guideline1 and the British Society for Haematology guideline2) and the presentation by Prof. Jane Apperley during the 2021 BHS GAM, this article will give an overview of the latest developments in the therapeutic CML landscape and address a range of the persistent unmet needs in the diagnosis and treatment of CP-CML.
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