Journal issues > Issue 8, December 2024 > Diagnosis of a T-cell prolymphocytic leukaemia in a 78-year-old asymptomatic patient

Diagnosis of a T-cell prolymphocytic leukaemia in a 78-year-old asymptomatic patient

By: O. Mortelé PhD, K.L. Wu MD, PhD, K. Verboom PhD, P. De schouwer MD, E. Heylen PhD

SUMMARY

This case report outlines the diagnosis and management of T-cell prolymphocytic leukaemia (T-PLL) in a 78-year-old asymptomatic woman. The leukaemia rapidly progressed within five months, leading to a hyperleukocytosis of 305 × 10⁹/L and thrombopenia suggestive for bone marrow involvement. Diagnostic assessments included peripheral blood analysis, immunophenotyping, cytogenetics and molecular analysis according to the unified diagnostic criteria of the T-PLL International Study Group (T-PLL-ISG). Bendamustine treatment was initiated resulting in a significant decrease in leucocytosis. In the past nine months, the patient has received six cycles of bendamustine and has remained asymptomatic to date.

(BELG J HEMATOL 2024;15(8):325–8)

To read the full artice you have the following options:

* (only possible for healthcare professionals with RIZIV/INAMI/MATRICULE working in the field of Hematology in Belgium and Luxembourg with prescription authorisation)

Purchase this article for €3.03

** (for healthcare professionals with prescribing authorisation working outside the field of Hematology in Belgium and Luxembourg as well as those without prescribing authorisation working as healthcare professional in Hematology in Belgium and Luxembourg, plus persons without prescription authorisation working outside Belgium and Luxembourg, plus healthcare professionals with prescribing authorisation outside Belgium and Luxembourg plus non-healthcare professionals from outside or inside Belgium or Luxembourg)

Top