Journal issues > Issue 3, September 2014 > MicroRNAs: new actors in acute myeloid leukaemia

MicroRNAs: new actors in acute myeloid leukaemia

Summary

Despite their small size, the impact of microRNAs in acute myeloid leukaemia seems to grow with every microRNA-related publication. Aberrant expression of microRNAs and oncogenic and tumour suppressor properties of microRNAs may contribute to the biology of acute myeloid leukaemia. As we performed for miR-29b, a critical step is to identify target genes and pathways deregulated by microRNAs during leukemogenesis. We are just starting to understand the clinical impact of microRNAs in acute myeloid leukaemia and to emphasise future microRNA-targeted therapeutic strategies. These small new actors may become important clinical contributors for the diagnosis, prognosis and treatment of acute myeloid leukaemia.

(BELG J HEMATOL 2014;5(3):110–12)

To read the full artice you have the following options:

* (only possible for healthcare professionals with RIZIV/INAMI/MATRICULE working in the field of Hematology in Belgium and Luxembourg with prescription authorisation)

Purchase this article for €3.03

** (for healthcare professionals with prescribing authorisation working outside the field of Hematology in Belgium and Luxembourg as well as those without prescribing authorisation working as healthcare professional in Hematology in Belgium and Luxembourg, plus persons without prescription authorisation working outside Belgium and Luxembourg, plus healthcare professionals with prescribing authorisation outside Belgium and Luxembourg plus non-healthcare professionals from outside or inside Belgium or Luxembourg)

Top